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Quantitative proteomics of 20 recombinant human proteins. Frequency of tandem mass spectra assigned to tryptic peptides in 20 recombinant human proteins (gene symbol). The results are shown as a peptide heat map representation for each of the 20 proteins. Each protein was present at equimolar abundance in the mixture. Intensity of red indicates abundance of tryptic peptides characterized by tandem mass spectrometry. Blue represents a tryptic peptide of 1250 Da. Each of the 20 proteins contained one or more peptides of this mass, but of a different primary sequence. Abscissa scale indicates the number of amino acid residues. (From Bell et al. 2009; reprinted, with permission, from the author and Nature Publishing Group © 2009.)

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