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1. Abbreviations: A Baseline, B Increasing minute ventilation, C Begin moderate hyperventilation with target PaCO2 4–4.7 kPa, D After moderate hyperventilation for 50 min, E Return to baseline, etCO2 End-tidal CO2, MV Minute ventilation (L/min), PaCO2 Partial pressure arterial carbon dioxide (kPa), PaO2 Partial pressure arterial oxygen (kPa)
2. Data are expressed as mean (SD)
3. * p < 0.05 compared with A
4. § p < 0.05 compared with B
5. ¶ p < 0.05 compared with C
6. Ŧ p < 0.05 compared with D